The Council of the IRPS is happy to present as the Spring 2020 ‘Publications from the membership’ two Perspectives based on Neuropeptide Workshops that are direct ‘legacy proceedings’ from RegPep2018.
The first represents the proceedings of a Workshop held in Bethesda Maryland under the auspices of the National Institute of Mental Health named “Regulatory Peptides: Emerging Neurotranslational Opportunities”. The Workshop featured two dominant themes: that peptide neurotherapeutics might be developed best via a ‘virtual drug pipeline’ involving micropharma, academia, and the pharmaceutical industry and the related idea that the field as a whole might move more quickly to validate or reject the potential of various CNS peptidergic targets by sharing the risk across stakeholders involved in advancing new therapies through pre-competitive consortia.
The second represents most directly the efforts of the IRPS in transitioning to a new and more effective position of leadership, on behalf of its members, in the field of regulatory peptides. The proceedings of this workshop, also primarily translationally oriented, are included as a Perspective in “Regulatory peptides as systems biology: A new area of translational and reverse-translational neuroendocrinology”. It summarizes the guiding principles of IRPS and projects them into the future, and, importantly, contains the announcement of IRPS’s adoption of JOURNAL OF NEUROENDOCRINOLOGY as the parent journal for the IRPS. After some debate among members of the Council, it was decided that the scope and mission of JNE best captures the total systems interest, from gut to brain, and including nervous and endocrine regulation and diseases arising from their dysregulation, of our Society. It is our sincerest hope that members will support our Society’s official journal via publishing of your most excellent science in it, rigorous peer reviewing for it, and avid reading of its contents including that provided by members of the IRPS.
The IRPS calls attention of membership to a comprehensive review of neuropeptide (Oxt and AVP) dendritic release and its function by Brown and colleagues, and please see the feature “Bigger Picture” describing some of the general implications of this review for regulatory peptide function.
